Rat Anti-Mouse CD94-BIOT MBS673583 from MyBioSource.com

Product Specs
ItemRat Anti-Mouse CD94-BIOT
CompanyMyBioSource.com
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMBS673583
Quantity0.5 mg
ApplicationsFlow Cytometry
Conjugate/TagBiotin (BIOT)
FormatBiotin (BIOT) Conjugate
ReactivityMouse
TargetCD94
IsotypeIgG2a kappa
Molecular Weight20,513 Da
Clone18d3
HostRat
Antibody TypeSecondary
ImmunogenMouse CD94 receptor subunit, Mr 70 kDa
The monoclonal antibody 18D3 reacts with the mouse CD94 receptor subunit, a 70kDa type II transmembrane glycoprotein. CD94 is expressed on the surface of NK cells, NK T cells and some memory phenotype CD8+ cells.2 When CD94 is paired with NKG2A, C, or E subunit, it binds the nonclassical MHC class Ib molecule Qa-1b and results in a CD94high population by flow cytometry.1, 2 Approximately half of NK cells do not express NKG2A, C or E; these cells express CD94 on the surface in a form that does not bind Qa-1b and is believed to be nonfunctional, producing a CD94low population by flow cytometry.1, 2 CD94 is thought to play a role in the adhesion and activation of the NK cell lineage
NCBI Full Gene Namekiller cell lectin-like receptor subfamily D, member 1
NCBI Gene AliasesCD94
ClonalityMonoclonal